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In this review, we formalize the concept of synthetic lipid biology

Therefore, in seeking to understand nAb activity in vivo, it is important to consider the limitations of the neutralization assay used

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This phenotype was explored in both mouse models and in vitro with an anti-IL-23 antibody to block IL-23 signaling where mice experienced prolonged survival and decreased tumor burden, and CD8 + cells in mice and in vitro showed enhanced cytotoxicity in the IL-23-depleted state [154] (Fig