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Immunotherapy in allergic rhinitis: its effect on the immune system and clinical symptoms

As MOTS-c activates AMPK and NRF2, it also indirectly suppresses the mTOR (mechanistic target of rapamycin) pathway, the master growth and anabolism regulator that, when chronically overactivated, accelerates the accumulation of senescent cells

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Lamprea-Montealegre, MD, MPH, PhD, a clinical instructor in the division of cardiology and a postdoctoral research fellow at the Kidney Health Research Collaborative at the University of California, San Francisco, and colleagues performed a cross-sectional analysis using data from the Veterans Affairs Corporate Data Warehouse

In the present study, GDF15 levels did not correlate significantly with clinical indices of disease severity, including FIQR, WPI, or SSS scores