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During fasting, this is of special importance as most tissues other than the brain can thereby utilize fatty acids directly to generate energy

(PubMed) Hager K, Marahrens A, Kenklies M, Riederer P, Munch G

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Rhamnetin decelerates the elimination and enhances the antitumor effect of the molecular-targeting agent sorafenib in hepatocellular carcinoma cells via the miR-148a/PXR axis

Prior pancreatitis, gallbladder disease, kidney problems, diabetic retinopathy, significant gastrointestinal symptoms, and use of insulin or sulfonylureas may require closer risk assessment rather than automatic exclusion