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Anxiolytic and antidepressant effects of intracerebroventricularly administered somatostatin: behavioral and neurophysiological evidence

Large scale phenotype imputation and in vivo functional validation implicate ADAMTS14 as an adiposity gene

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The declining plasma concentration provides a quantitative framework for researchers designing dose-response studies, as physiologically relevant in vitro concentrations should bracket the 200-500 nM range to model the young-to-aged spectrum