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Furthermore, cAMP-dependent mechanisms acting through PKA, and the exchange protein directly activated by cAMP (EPAC) inhibit ATP-dependent potassium channels and increase the activity of calcium channels

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Importantly, the risk of brachial plexus injury secondary to MPNST should be considered before patients are treated with radiotherapy for the primary tumor lesion, and long-term follow-up along with neurological examination of patients after radiotherapy is necessary