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This mechanism is believed to play a key role in the pathogenesis of TED and is the basis for emergent therapeutic alternatives in patients with TED and, maybe, dermopathy

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(29) showed the interaction between the level of proinflammatory cytokines and ROS generation in the model of gastric ischemia-reperfusion and concluded that a decrease of ROS production caused the inhibition of adhesion molecules expression, leads to the decrease of mucosal neutrophil infiltration

Obesity and insulin resistance are the main factors that cause this reduced fertility [21-23]