Results of the first phase 3 trial comparing orforglipron with oral semaglutide found that patients with diabetes lost on average 6-8% of their body weight with orforglipron, compared with 4-5% on semaglutide
For the full mechanism explainer including how GcgR's glucose-raising effect is offset by GLP-1R co-agonism, see the Glucagon Receptor Explained entity page
It helps refine texture, reduce the appearance of fine lines, and improve overall skin tone
Both of these are very strong heat-clearing and toxin-resolving herbs
Ingredients: 1 cup cooked quinoa 1 cup canned chickpeas, rinsed cucumber, diced cup cherry tomatoes, halved cup red onion, finely chopped Dressing: 2 tbsp olive oil + juice of 1 lemon + 1 tsp Dijon + pinch of salt & pepper Directions: Toss everything together, refrigerate for lunches all week. Bitter Greens Saut Why