Although some studies are well controlled and show positive results, the efficacy of the GFCF diet is still questioned because most of the published research had methodological flaws such as lack of a control group, administration of medications and supplements in conjunction with the dietary intervention, Diversity of diagnoses of participants (individuals with ASD and Rett syndrome), limited number of participants, wide age range of participants, male and female participants in the same group, heterogeneous nutritional interventions and the effectiveness of the diet in most studies was assessed by psychological tests and behavioral observations directed at teachers, therapists and relatives of individuals with ASD [148,149]
GLP-1 receptor agonist medications like semaglutide mimic it: they slow gastric emptying so you feel full longer, dampen the appetite signals that drive between-meal eating, and improve the way your body handles blood sugar
The mechanism underlying these prosocial effects involves Melanotan II's activation of melanocortin-4 receptors (MC4R) located on oxytocin neurons in the paraventricular nucleus of the hypothalamus
If youre interested, talk to your doctor.
In a mouse model of inflammation, the decrease of LPS-induced paw edema by DATS was associated with reduced serum concentrations of the pro-inflammatory cytokines, TNF-, IL-6, and monocyte chemotactic protein-1 (MCP-1) (36)
