In a Phase II trial, pelacarsen reduced Lp(a) levels by 3558% depending on the dose, with no significant differences in safety indicators compared with the placebo
It is used together with diet and exercise to improve blood sugar control in adults with type 2 diabetes mellitus
Resistance training and adequate protein intake (at least 1 gram per pound of ideal body weight) are essential to minimize muscle loss
ChaC-like enzymes act specifically on GSH, GGACT enzymes act on -glutamylamine amino acids, and GGCTs have a broader activity towards -glutamyl amino acids in general
Furthermore, key immune and blood parameters, such as white and red blood cell count, hemoglobin, hematocrit, and platelet count, are recorded, providing insights into infections, inflammation, and overall health status