In its National Poison Data System alert, Americas Poison Centers noted that some people reported accidentally taking 10-times the recommended dose due to confusing measurement units while using a syringe. And people who are eager to lose extra weight before a wedding or a vacation, for example may choose to self-administer a higher-than-recommended dose, said Arthur Caplan, a bioethics professor at New York Universitys Grossman School of Medicine
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In SURMOUNT-5, gastrointestinal adverse events occurred primarily during dose escalation
Current guidelines from the American Society for Metabolic and Bariatric Surgery (ASMBS) and International Federation for the Surgery of Obesity (IFSO) support consideration in patients with BMI 35 kg/m regardless of comorbidities, or BMI 30-34.9 kg/m with metabolic disease
It is well known that inflammation is linked with breakdown of the blood-retinal barrier, which results in vascular dysfunction and edema