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[15] [16] The European Medicines Agency (EMA) and MHRA have not issued specific warnings about bone health concerns with these medications

The same guideline also tells you that you should use the codes if the patient is receiving a medication for an extended period as a prophylactic measure or as treatment of a chronic condition or a disease requiring a lengthy course of treatment (such as cancer). You should not assign one of the Z79 codes for medication being administered for a brief period of time to treat an acute illness or injury. The guideline does not define extended period with a particular timeframe, so you should look to the patients condition and consult with your pediatrician before assigning a code from the group

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10.1056/NEJMoa1305889

However, histamines are most well-known for triggering inflammatory responses when potential invaders enter your body