PGP is a stabilising motif derived from biological observation: it resists most endopeptidases and aminopeptidases thanks to rigid prolines (pyrrolidine cycle)
J Cell Physiol 230:30093018 Yu J, Shi YC, Ping F, Li W, Zhang HB, He SL, Zhao Y, Xu LL, Li YX (2021) Liraglutide inhibits osteoclastogenesis and improves bone loss by downregulating Trem2 in female type 1 diabetic mice: findings from transcriptomics
Option Analysis Option (A): Primaquine generates reactive oxygen species (ROS) via its metabolites, increasing demand for NADPH to regenerate reduced glutathione (GSH) for antioxidant defense
Injection Maintenance After initial therapy (23 months, 12 injections weekly), maintenance injections are taken once every 24 weeks
Flushing and Warmth Some patients describe a sensation of warmth, flushing, or mild facial redness after injection