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doi: 10.1371/journal.pone.0179860

Disrupting MYSM1 (Myb like, SWIRM and MPN domains 1), a histone deubiquitinase, can compromise human HSC function, mimicking the bone marrow failure seen in patients, by triggering lipid peroxidation and ferroptosis [203]

Glutathione and immune system support: Mechanisms and benefits in aging populations

Moreover, early studies on HIV-1-infected subjects associated GSH deficiency with a poor lymphocytic response and impaired survival following HIV-1 infections 28,29,30 , implying a role for GSH in disease