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Abbreviations AF: Annulus fibrosus ASC: Adipose-derived stem cell BMP-2: Bone morphogenetic protein-2 BMSC: Bone marrow-derived stem cell CD: Chondrodystrophic CLC: Chondrocyte-like cell CTGF: Connective tissue growth factor DH: Disc height ECM: Extracellular matrix EP: End plate GAG: Glycosaminoglycan GDF-5: Growth and differentiation factor-5 IGF-1: Isulin-like growth factor-1 IVD: Intervertebral disc MSC: Mesenchymal stromal (stem) cells MMP: Matrix metalloproteinase MRI: Magnetic resonance imaging NC: Notochordal cell NCCM: Notochordal cell conditioned medium NCD: Non-chondrodystrophic NP: Nucleus pulposus NPPC: Nucleus pulposus progenitor cell

Constipation, indigestion, and loss of appetite are also common side effects

Everyone expects these medications to be magic, says Hans Schmidt, director of the Center for Weight Loss & Metabolic Health and chief of bariatric surgery at Hackensack University Medical Center in New Jersey

Nightmares can be associated with a number of neuropsychiatric and neurodegenerative disorders

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