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Details of the CpG island size, location, and CpG content are described in the supplementary methods (Supplementary Table S3)

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Support for Bone Density and Joint Integrity : Growth hormone pulses initiated by this combination stimulate osteoblastic activity and calcium retention , improving bone mineral density and supporting joint health

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Consent for publication All authors agree to publish this review

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This synergy may result from GHK-Cu stimulating glycosaminoglycan production and promoting collagen synthesis, while HA may reduce collagen degradation by scavenging reactive oxygen species and inhibiting matrix metalloproteinases

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