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Common adverse effects include nausea, vomiting, diarrhoea, and a modest increase in heart rate, consistent with the GLP-1 receptor agonist class

Canadian Agency for Drugs and Technologies in Health (CADTH): Semaglutide Reimbursement Review: CADTH reimbursement guidance used by provincial drug plans for semaglutide.

The impact of saw palmetto has not been extensively studied, but laboratory studies subjecting sperm to high levels of saw palmetto were noted to have a negative impact on sperm motility