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159 One major way it produces this effect is by sponging up destructive reactive nitrogen species, such as peroxynitrite

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There are also reports of differing levels in mtDNA expression, possible mitochondrial depletion, and deletions/copy number variations in small cohorts (118, 119)

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Endoplasmic reticulum stress related factor IRE1 regulates TXNIP/NLRP3-mediated pyroptosis in diabetic nephropathy