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Therapeutics targeting oxidative stress hold great promise for the treatment of DR but have not yet been translated into clinical practice

The study found increased blood flow to exercising muscles, with improvements ranging from 20-35%

Singanayagam et al., 2022

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Now, however, it is recognized that these RBC contain a coagulum of hemoglobin which has separated from the membrane, often leaving an unstained non-hemoglobin-containing cell membrane (i.e., having the appearance of a bite removed from the cell)