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FIGURE 1 TABLE 2 Comparison of tacrolimus (Tac) pharmacokinetic variables in whole blood and their corresponding correlations after morning Tac dose (012 h) and after night Tac dose (1224 h) of twice-daily Tac formulation

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The transcytotic pathway, in contrast, involves calcium-dependent engagement of the cytoplasmic tail of FcRn by calmodulin, and is controlled by Rab25 and myosin VB [79, 80]

The response rate was equally striking: 91.7% of participants achieved at least 10% weight loss