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Future work will be necessary to perform similar studies in patients with obesity by comparing new generation anti-obesity GLP-1RAs with other anti-obesity medications in patients with obesity

However, future studies will be required to address such a possibility

A diferencia de la modificacin LR3 que agrega aminocidos para extender la molcula el DES IGF-1 los elimina, y las consecuencias de esa delecin son farmacolgicamente significativas en dos aspectos: Afinidad de unin al IGFBP-3 dramticamente reducida la regin N-terminal del IGF-1 es importante para la unin al IGFBP-3

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