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In addition to choline, increased intake of dietary L-carnitine was also demonstrated to accelerate atherosclerosis in mice, which was observed to be linked with TMAO-induced inhibition of reverse cholesterol transport (Koeth et al., 2013)

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Conversely, the resident microbiota and its metabolites can influence the hosts response to GLP-1 RA therapy, a complex guthormone axis with potential implications for personalized treatment (12, 13)

The ASCQR Program affected payment rates beginning in CY 2014 and, under this program, there is a 2.0 percentage point reduction to the hospital market basket update factor for ASCs that fail to meet the ASCQR Program requirements