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Most protocols range from 612 weeks, with reassessment every few months

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The effect of thiamine occurred independent of control of hyperglycaemia, blood pressure and statin/fibrate therapy, suggesting that high dose thiamine therapy may produce improvements in the prevention of dyslipidaemia and diabetic nephropathy in addition to those produced by current therapy for control of hyperglycaemia, blood pressure, cholesterol and lipids

It is meant to be used in combination with a healthy diet and regular exercise to manage diabetes effectively