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Acta Pharmacol Sin 23:412422 Sikiric P, Seiwerth S, Brcic L et al (2006) Stable gastric pentadecapeptide BPC 157 in trials for inflammatory bowel disease (PL-10, PLD-116, PL 14736, Pliva, Croatia)

NSAIDs primarily reduce inflammation by inhibiting cyclooxygenase enzymes (COX-1 and COX-2), which are responsible for the production of prostaglandins, which are involved in the inflammatory response, including the promotion of pain, fever, and tissue damage