Presumably, other types of TmGst could play a role in detoxifying other xenobiotics, including antifungal drugs
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Gut healing applications align best with oral delivery
Further, cells in the absence of WRN have defects in DNA double-strand breaks, especially those bound with DNA replication fork arrest
Trends Cancer 6(12):10181030 Reimertz C, Kogel D, Rami A, Chittenden T, Prehn JH (2003) Gene expression during ER stress-induced apoptosis in neurons: induction of the BH3-only protein Bbc3/PUMA and activation of the mitochondrial apoptosis pathway