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There have been postmarketing reports of acute kidney injury, in some cases requiring hemodialysis, in patients treated with liraglutide [see Adverse Reactions (6.2)]

Principal components analysis on genes related to inflammasome complex and microglial activation in the hypothalamus of obese mice treated with semaglutide (GLP-1 analog) Brain Res

Prioritize whole foods with high-quality protein, colorful vegetables, healthy fats, and a variety of textures and flavors to encourage eating even when appetite is low

These receptors exist throughout the body, including in pancreatic tissue

Importantly, these criteria intentionally exclude peptide systems for which multiple well-designed human studies have demonstrated a lack of efficacy or unacceptable safety profiles