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Regul Peptides (1995) 58:149156

Gastrointestinal Effects: Duration, Severity, and Individual Variation GI side effects are semaglutide's most common short-term concern

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B vitamins B vitamin deficiency can independently cause oral symptoms including dry mouth, glossitis (tongue inflammation), and angular cheilitis (cracked corners of the mouth)

Glycine also contributes to the production of glutathione, a powerful antioxidant, and creatine, which supplies energy to muscles