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Intarcia , a US biotech, had to terminate two Phase III trials in January after the FDA rejected its drug-delivery device for type 2 diabetes

A new gastric juice peptide, BPC: an overview of the stomach-stress-organoprotection hypothesis

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Vyvanse is FDA-approved for this use, while topiramate is typically prescribed off-label

For renal impairment, although most GLP-1 agents have minimal renal clearance, impaired kidney function increases the risk of adverse events such as dehydration from vomiting or decreased drug clearance in polypharmacy