Holst, a University of Copenhagen professor, discovered that GLP-1 acts as an incretin hormone, stimulating insulin secretion in response to food
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Disappears upon discontinuation Insomnia if taken late: avoid taking after 4-5 PM, especially combined with caffeine Headaches rare at high doses If you experience digestive effects, split the dose (1 capsule morning + 1 capsule midday) or take during a meal generally improves tolerance
Zhao LD, Bie LY, Hu L, Zhu ZH, Meng XH, Cong LL, Zhang S, Ma N, Xiao JH
The Science of GLP-1 and Gastrointestinal Function To answer the question of whether semaglutide can influence IBS, we must first understand what the GLP-1 hormone does naturally in our bodies