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Keeping records of which peptides were active during different periods helps correlate changes with specific additions

This is a hard contraindication, not a caution

Indeed, cell-mediated immunity requires that protein antigens be first degraded in the endocytic vesicles of APCs (eg, macrophages, dendritic cells), so that the smaller peptides can be presented on the cell surface by the major histocompatibility complex to activate proliferation of antigen-specific T cells

Once B12 deficiency is confirmed, the doctor will want to know why someone has B12 deficiency

Current findings are derived from in vitro and preclinical experimental models, with mechanisms remaining under active investigation