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Semaglutide is a GLP-1 (glucagon-like peptide-1) weight loss medication that comes as three brand-name drugs, Wegovy, Ozempic, and Rybelsus, each approved by the U.S

Here are some of the findings: American Journal of Clinical Nutrition (2016) : In this study, participants who took 2,000 mg of L-Carnitine per day experienced a noticeable increase in fat oxidation (fat burning), especially when paired with regular exercise

Always factor this into your experimental design

Resistance training three to four times per week during your treatment phase builds metabolic muscle that burns calories at rest

This evidence supports semaglutide as a long-term maintenance medication, not a 12-week intervention