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Related reads: References Nassar, G

Dose, route, timing, and model artifacts Preclinical doses (for example, T4 at 630 mg/kg in rats, or BPC-157 at microgram-to-nanogram-per-kilogram ranges) do not translate to humans by simple scaling, and route and timing strongly shaped the reported outcomes

The dose-response relationship with sleep disruption appears roughly linear: higher doses correlate with more pronounced effects

[2] In the molecular characterization of the receptor, radiolabeled MK-0677 bound the cloned receptor with high, sub-nanomolar affinity, directly confirming MK-677 as a GHS-R ligand