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It really highlights the need for further investigation into their ocular safety profile, first study author Reut Shor, MD, of the Department of Ophthalmology and Vision Sciences at the University of Toronto, Canada, told Healthline

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After entering the general circulation, GLP-1 binds to G-protein coupled receptors in pancreatic and extra-pancreatic tissues, including the enteric and central nervous systems, kidney, lung, heart, and endothelial and vascular smooth muscle cells [27]