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It also activates lysyl oxidase (LOX), the copper-dependent enzyme responsible for collagen and elastin crosslinking in the extracellular matrix

Extensive research has indicated that metformin exhibits notable effectiveness in addressing PCOS-related complications, including cardiovascular diseases, MASLD, MS, and EC, underscoring its significant potential to enhance long-term health outcomes in individuals with PCOS

These efforts build on the Association's longstanding commitment to evidencebased guidance and are intended to support earlier, more consistent and more equitable integration of brain health into routine care

Moreover, the transferred DDA-GSH-AuNCs maintain their fluorescence properties in all evaluated organic solvents as shown in Fig