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So, what actually disrupts the MMC and causes it to malfunction

All content focuses on in-vitro research applications only

T4 DNA ligase is one among the commonly used ligases in this process that catalyzes the ligation of the 3-hydroxy and 5-phosphate ends of a ssDNA molecule with the help of a splint DNA strand (112)

Kuroki T, Tanaka R, Shimada Y, Yamashiro K, Ueno Y, Shimura H, Urabe T, Hattori N (2016) Exendin-4 inhibits matrix metalloproteinase-9 activation and reduces infarct growth after focal cerebral ischemia in hyperglycemic mice