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Other chronic conditions (heart, kidney, liver): These can affect energy balance, fluid retention, and nutrient processing, sometimes slowing visible weight changes

HIF-1 is a transcription factor that controls several genes required to maintain a balance between oxygen supply and metabolic demand 53

Rare mitoses may be seen, but they should not be atypical or present at the base of the lesion

A weight loss of 35% can mitigate hepatic steatosis, while 7% and 10% weight reductions have been shown to resolve MASH and improve fibrosis after one year, respectively 111,112

To apply this remedy, I use about three to four drops of DMSO directly on the lipoma and follow it with a squirt of aloe vera