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Uptake: LipoDuo demonstrated 19-fold higher cellular uptake than plain glutathione, peaking at 6 h (45 % v

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However, most REES-based studies of IDPs were conducted very recently and therefore did not contribute to the establishing of the IDP field [for example, REES was used for analysis of -synuclein and amyloidogenic k-casein in 2013 and 2014, respectively (Jain et al., 2013

Research on glycocalyx protectants (such as phillyrin and sphingosine-1-phosphate) is still in its early stages and relies on animal models and in vitro experiments [76, 121]

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