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It is crucial for DNA repair, gene expression regulation, and maintaining overall cellular health

NVU Neurovascular unit (endothelial cells, astrocytes, pericytes, ECM and neurons) OGD Oxygen and glucose deprivation (to mimic ischemia) P-gp P-glycoprotein TEER Transendothelial electrical resistance (TEER) TJs Tight junction proteins

Subsequently, activated CD8+ T cells migrate to and enter the tumor, resulting in better tumor control and long-lasting memory responses with anti-PD1 therapy (252)

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