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The BBC has contacted the FDA for comment

The FDA approved semaglutide for chronic weight loss management in adults with a body mass index (BMI) of 30 kg/m2 or higher or those with a BMI of 27 kg/m2 or higher and at least one weight-related ailment, such as high cholesterol, high blood pressure, or type 2 diabetes

On 2.4mg, average weight loss is 17.5%

This manuscript and LL and DRW were supported by EPSRC (grant number EP/T005556/1)

Patients with CD may present orofacial granulomatosis, as symptomatic oral disease, and other oral manifestation derived from qualitative changes in salivary composition (32)