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Finally, obese mice lost weight more effectively when dexamethasone and GLP- 1 were conjugated than when GLP- 1 was used alone [142]

Why diet and exercise alone may not work Diet and exercise have long been the gold standard in turning the tide on weight gain, though genetics, medical conditions and socioeconomic factors can make losing weight difficult to impossible

J., Bai, S

doi: 10.1111/dom.12849 32 SimRChongCWLoganadanNKFongAYYNavaravongLHusseinZet al

GLP- 1 receptor activation has longer-term consequences, such as increased b cell proliferation and neogenesis along with cytoprotective (non-insulinotropic) effects [45,46,47,48,49,50,51]