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Assuming the remaining Phase 3 data continues to support both safety and efficacy, and the FDA review process moves forward without delays, industry projections currently point to a possible late 2026 to 2027 timeline

Updated result (January 26, 2026): Roche announced full 48-week Phase II results from the CT388-103 trial (NCT06525935, n=469)

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A person burning 2,800 calories daily who drops to eating 1,500 calories faces a 1,300-calorie deficit, compared to a sedentary person burning 2,000 calories with the same food intake facing only a 500-calorie deficit

Comparing your results to averages: where do you stand Here is a reference framework for understanding whether your results are on track, above average, or below expected