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Histone deacetylase sirtuin 6 (SIRT6), a member of the sirtuin family, plays critical roles in metabolic regulation, apoptosis, cell survival, development, inflammation, and aging [13]
In a busulfancyclophosphamide model of premature ovarian failure, tail-vein infusion of human EnMSCs homed to the stroma, replenished germline stem-cell pools, normalised estrous cycling within four weeks and generated fertile litters, confirming that niche renewal can reverse chemotoxic damage [187]
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Science 385 , eadl5763 (2024)
Fischer V, Haar J, Greiner L et al (1991) Possible role of free radical formation in clozapine (clozaril)-induced agranulocytosis
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