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Linking the metabolic state and mitochondrial DNA in chronic disease, health, and aging

Thymosin beta-4 is a defined 43-amino-acid endogenous protein, while TB-500 is usually a synthetic fragment built around its actin-binding domain (Ac-LKKTETQ)

Our findings confirm that Vit D and N-3 PUFAs exhibit substantial synergistic neuroprotective abilities that might be mediated through synergistic VDR upregulation, providing a promising dietary intervention against MSG-induced excitotoxicity and highlighting their broader implications for supporting cognitive health and mitigating the adverse effects of other neurotoxins

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