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One such study found that GLP-1 elevates intracellular cAMP, subsequently activating protein kinase A (PKA), which in turn inhibits RhoA/ROCK signaling, resulting in the disassembly of glucotoxicity-induced stress fibers 6

Code availability The scripts used to analyse the RNA-seq data are available at GitHub ( References Locke, A

Nyberg J, Anderson MF, Meister B et al (2005) Glucose-dependent insulinotropic polypeptide is expressed in adult hippocampus and induces progenitor cell proliferation