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Participants on the highest dose (15 mg) achieved an average weight reduction of 22.9% over three years, marking one of the longest documented sustained weight loss effects in obesity pharmacotherapy

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HLA-Cw6 and other HLA-C alleles, as well as MICB-DT, DDX58, and TYK2 genetic variants associate with optimal response to anti-IL-17A treatment in patients with psoriasis