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The search criteria included the terms: HE, minimal HE (MHE), definition, classifications, epidemiologic panorama in the world and in Mexico, pathophysiology, risk factors, clinical manifestations, diagnosis, differential diagnosis, treatment, primary and secondary prophylaxis

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Additionally, microglial activation is associated with a morphologic transition from ramified to amoeboid-like, adopting a phagocytic phenotype (Woodburn et al., 2021)

If a Klow product contains GHK-Cu, KPV, or other skin-relevant peptides, you still need to separate the research on each ingredient from the marketing claim on the blend