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Given the increased appreciation of the reciprocal nature of dyslipidemia, obesity, dysglycemia and liver disease, including nonalcoholic fatty liver disease (NAFLD) and traditional risk factors, a new classification of metabolic (dysfunction) associated fatty liver disease (MAFLD) has emerged (3)

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Tirzepatide contains non-conventional amino acid residues at positions two and 13 (-amino isobutyric acids), and the C-terminus is amidated (Coskun et al