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PLoS ONE 11:e0162318 Siegel R, Naishadham D, Jemal AA (2013) Analysis of fiducials implanted during EUS for patients with localized rectal cancer receiving high-dose rate endorectal brachytherapy

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Transferrin (Tf) mediates iron delivery to cells via the transferrin receptor (TfR), and disruption of this process can lead to iron overload and ferroptosis

As a powerful antioxidant, glutathione helps protect mitochondria, the cellular structures where fatty acids are oxidized to produce energy, from oxidative damage

Following DNA damage, the cell cycle can be transiently arrested to allow for DNA repair or activation of pathways leading to programmed cell death (apoptosis) when the damage cannot be repaired (29)