33-35 Although single studies evaluating the efficacy of metformin for treatment of hirsutism in patients with PCOS have shown potential benefits, 36-38 meta-analyses showed no significant effects of metformin compared to placebo or oral contraceptives and decreased benefits compared to spironolactone and flutamide
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Similarly, Saxenda discontinuation should be discussed with the prescribing clinician
Munoz-Mantilla D