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Can cause high potassium, low sodium, and low blood pressure

Ozempic is approved for the treatment of type 2 diabetes, while other brands, such as Wegovy, are prescribed for weight management

GPX4 is required for repression of both canonical CASP1- and non-canonical CASP11-mediated cleavage of GSDMD 56 , indicating that GSH-dependent antioxidant systems do not only inhibit inflammasome assembly but also limit the oxidized membrane environment that favors gasdermin pore formation

Coordinating CenterIRCCS - Mario Negri Institute for Pharmacological Research, Clinical Research Center for Rare Diseases Aldo e Cele Dacc

Three mammalian DNMTs have been defined: DNA methyltransferase 1 (DNMT1), DNA methyltransferase 3 alpha (DNMT3A), and DNA methyltransferase 3 beta (DNMT3B)