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Reciclaje de cistena a partir de glutatin conjugado mediante -glutamiltranspeptidasa (GGT) en el ciclo de -glutamil Regeneracin del glutatin oxidado (GSSG) a GSH por la glutatin reductasa (GR) La mayor parte del GSH (80-85%) se almacena en el citosol, un 10-15% en las mitocondrias (con una concentracin igual entre matriz y citosol, por lo que requiere sistemas de transporte especficos) y una pequea parte en el retculo endoplsmico (RE)